Unified proteomics analysis platform

DeepHeal ProteoMap

Proteomic Phenotype Connectivity Map — Proteomics-based Drug Response Phenotype Prediction

Project a single perturbation-proteomics profile into the complementary DeepHeal and DRP reference spaces; estimate antineoplastic response, assign a drug response phenotype, identify the closest reference compounds, and report the CPS-6 antiproliferative-potency score with its reference percentile.

Template CSV
Single-panel input
log2FC proteomics profile
DeepHeal latent map
similarity and projection
DRP report
phenotype and interpretation
Proteomics Analysis Console
DeepHeal classification
Potential anticancer
Average / SupCon
95% / 40%
DRP assignment
C4
CPS-6 potency score
14.4 (P56.1)

One front end for DeepHeal and DRP

A unified public entry point connecting one perturbation-proteomics input to complementary DeepHeal and DRP analyses.

Proteomics Input

Upload a log2FC protein panel or matrix with sample annotation for downstream DeepHeal and DRP / CPS-6 analyses.

DeepHeal Projection

Project proteomic profiles into the HCT116-derived DeepHeal response space and report Average/SupCon branch scores, model votes, regulated and contributing proteins, and pathway evidence.

DRP / CPS-6 Analysis

Project query profiles onto the HepG2-derived 10-DRP landscape, report DRP assignment and confidence, and calculate the CPS-6 potency score with its reference percentile.

Phenotype-based Interpretation

Return the closest reference agents, proteomic similarity, pathway context, and mechanism hypotheses.

One upload, two complementary analysis routes

Upload one perturbation-proteomics profile and explore two complementary reference spaces for discovery and interpretation.

DeepHeal route

  • DeepHeal response-space projection
  • Average and SupCon branch scores
  • Model-vote antineoplastic classification
  • Top regulated and contributing proteins
  • Pathway enrichment and ranked driver evidence

DRP / CPS-6 route

  • Projection onto the 10-DRP landscape
  • DRP assignment and projection confidence
  • Closest reference antineoplastic agents
  • CPS-6 antiproliferative-potency score and percentile

Representative outputs from both analysis routes

Condensed previews based on the current live DeepHeal and DRP interfaces.

DeepHeal result preview

Representative output from the live DeepHeal analysis interface.

Classification
Potential anticancer
3 of 4 DeepHeal models call Antineoplastic
Average score 95%
Primary branch for tie resolution
SupCon score 40%
Mixed reference
Model votes 3 Antineoplastic · 1 Non-antineoplastic
Top regulated proteins
IFIH1 · ATP5F1E · HIVEP1
Top contributing proteins
APOB · ODC1 · FBXO5 · PSRC1 · ZFAND5
Supported functional modules
Cell cycle · PLK1 pathway · DNA replication

DRP result preview

Representative output from the live DRP analysis interface.

Assigned DRP
Confidence 71.48%
C4
NFκB/STAT3 inflammatory + EMT/angiogenesis
CPS-6 antiproliferative-potency score
14.4
Medium
Percentile vs 367 reference drugs P56.1
Similar drugs
Ranked Top-10
Mechanism-oriented interpretation
Phenotype-based

Natural products and TCM-ready analysis

The same DeepHeal / DRP front end can be used for self-measured natural products and traditional medicine-derived compounds when compatible proteomics data are available.

Shikonin / Alkannin
Ginsenoside Rh1 / Ginsenoside Rh2
Homoharringtonine / Cephalotaxine
Dioscin / Diosgenin

Ready to analyze a proteomics panel?

Open the unified application or sign in to upload a proteomics panel.